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Exploring The TikTok Trend: Can Magnesium And Vitamin D Alleviate Anxiety? Health News

In the world of viral TikTok trends, a recent video posted by user @tylerjohnwesley has garnered a whopping 16.3 million views, suggesting a potential remedy for anxiety. Tyler advocates for a daily regimen of 500 milligrams of magnesium glycinate and 125 micrograms (5,000 IU) of vitamin D3 to find solace from anxiety, coining it as "500 milli vanilli grams of peace."

According to Tyler, this unconventional hack transformed his lifelong struggle with anxiety, as he boldly declared, "I don't have anxiety anymore. Thirty years, anxiety my whole life. I don't have it anymore. Try it." Comments from users flooded in, with some sharing their own positive experiences. Jesseca Weeks proclaimed, "This is the first thing to actually help me," while jaymiekraft chimed in with, "Dude I started the exact same thing a few months ago. IT WORKS!!!!" Others expressed their curiosity and eagerness to try this anxiety-alleviating combination.

While the anecdotes from those who have embraced this regimen are encouraging, the burning question is whether there's any scientific validity to these claims. Can magnesium and vitamin D truly be effective tools in managing anxiety?

Understanding the Potential of Magnesium and Vitamin D

Although TikTok is not typically the go-to source for medical advice, Dr. Uma Naidoo, director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital and author of "Calm Your Mind With Food," has pointed out that there is "clear support for the role of vitamin D and magnesium in helping symptoms of depression and anxiety."

Dr. Naidoo explained the significance of vitamin D, a fat-soluble vitamin that plays pivotal roles in calcium absorption, bone growth, mineralisation, and bone remodelling. In the brain, it acts as a neuro-steroid, offering protection against depression and anxiety disorders. There is a well-established link between vitamin D deficiency and symptoms of depression, as well as heightened anxiety, making it a key player in regulating stress responses.

Magnesium, on the other hand, is a mineral that governs numerous biochemical reactions in the body, including protein synthesis and the function of muscles and nerves. This mineral is instrumental in regulating neurotransmitters responsible for mood regulation. Low magnesium levels have been associated with anxiety, ADHD, fatigue, and decreased libido. Magnesium deficiency can also lead to depression and lower dopamine levels, whereas supplementation can elevate these levels. Additionally, it has been demonstrated to improve sleep quality, hydration, muscle growth, and recovery, which are closely intertwined with mental health and the management of anxiety and depression.

The Right Approach to Supplementation

Before rushing to stock up on magnesium and vitamin D supplements, it is crucial to understand that supplementation alone may not serve as a universal remedy for anxiety and depression. Dr. Kara Kushnir, MSW, LCSW, founder and clinical director of A Work of Heart Counseling, emphasised that mental health is not governed by a singular magic solution. Instead, it often involves a combination of various factors, including therapy, medication, social support, exercise, hydration, nutrition, and stress management techniques.

Nonetheless, Dr. Kushnir underlined that, when administered appropriately under a physician's guidance, supplementation can potentially help mitigate symptoms of depression and anxiety. The optimal dosage varies among individuals and can be determined through testing performed by a healthcare provider.

Dr. Kushnir also highlighted the prevalence of deficiencies in magnesium and vitamin D, making supplementation a valuable option. However, it is essential to remember that these supplements are not a guaranteed panacea for mental health conditions.

The Role of Nutrient-Rich Foods

While supplements may offer benefits, Dr. Naidoo emphasised that a balanced diet of nutrient-rich foods remains the most effective approach to nurturing a healthy body and mind. Wholesome, nutrient-dense foods provide a wide array of macro- and micronutrients necessary for optimal mental health. The connection between the gut and the brain is enhanced by fibre-rich plant foods, offering powerful antioxidant phytonutrients and combating brain inflammation. Healthy fats fortify the brain against ageing stressors. Therefore, a well-rounded diet is crucial for sustaining peak mental health.


In conclusion, the TikTok trend promoting magnesium and vitamin D for anxiety finds support in scientific literature. However, it is essential to remember that anxiety is a multifaceted condition, and no single solution is universally applicable. While supplements can be beneficial, the optimal approach is a combination of various factors, including therapy, social support, and a balanced diet rich in essential nutrients. Always consult a healthcare provider for guidance on supplementation tailored to your specific needs.

Source: Healthline